Overview: Alzheimer's disease already affects an estimated 5.3 million Americans, and this number is expected to grow significantly in the coming decade. A critical goal of Alzheimer's disease research is to improve methods of early diagnosis, so that patients can be identified sooner and, therefore, obtain greater advantage from available therapies. This project aims to make early detection of Alzheimer's disease more accurate and accessible over the internet People: This project is led by Dr. Eugene Agichtein (Emory Math&CS and Biomedical Informatics), in collaboration with Dr. Elizabeth Buffalo (Yerkes and Emory School of Medicine) and Dr. Stuart Zola (Yerkes and Emory School of Medicine). Current contributors are Noah Adler, Zelma Gist, Dmitry Lagun, Dr. Allan Levey, Cecelia Manzanares, and JongHo Shin. Acknowledgements: This research is supported by the National Institutes of Health grant 1R01EB014266 and was previously supported by the Emory Alzheimer's Disease Research Center (ADRC) pilot grant.